Possible side effects with RYLAZE
Possible side effects
There are possible side effects with RYLAZE. The side effects are similar to what is experienced with other asparaginase therapies.
RYLAZE should not be given to people who have had:
- Serious allergic reactions to RYLAZE
- Serious swelling of the pancreas (experienced as stomach pain), serious blood clots, or serious bleeding during previous asparaginase therapy
RYLAZE may cause serious side effects, including:
- Allergic reactions (a feeling of tightness in the throat, unusual swelling/redness in the throat and/or tongue, rash, or trouble breathing), some of which may be life-threatening
- Swelling of the pancreas (experienced as stomach pain), which, if left untreated, may be fatal
- Blood clots (may be experienced as headache, arm or leg swelling, shortness of breath, or chest pain), which may be life-threatening
- Bleeding, which may be life-threatening
- Liver problems
Some of the most common side effects with RYLAZE include: liver problems, nausea and vomiting, bone and muscle pain, infection, tiredness, headache, fever with low white blood cell count, fever, bleeding, mouth swelling (sometimes with sores), pain in the abdomen, decreased appetite, allergic reactions, high blood sugar levels, diarrhea, swelling of the pancreas, and low levels of potassium in your blood.
RYLAZE can harm your unborn baby. Inform your doctor if you are pregnant, planning to become pregnant, or nursing. Females of reproductive potential should use effective contraception (other than hormonal contraceptives) during treatment and for 3 months following the final dose. Do not breastfeed while receiving RYLAZE and for 1 week after the final dose.
These are not all the possible side effects of RYLAZE. For more information, ask the healthcare provider. Tell them if there are any side effects that are bothersome or that do not go away.
- Like other asparaginase therapies, RYLAZE may cause allergic reactions. Seek medical advice immediately if symptoms of an allergic reaction occur.
Patients are also encouraged to report negative side effects of prescription drugs to the Food and Drug Administration (FDA). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Patients may also report side effects to Jazz Pharmaceuticals at 1-800-520-5568.